1. How to submit my research paper? What’s the process for publication of my paper?
The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or .pdf format to the submission email: jomb@ejournal.net.
2.Can I submit an abstract?
The journal publishes full research papers. So only full paper submission... [Read More]

In Vitro Anti-Inflammatory Activities of Red Gemor (Nothaphoebe cf Umbelliflora)

Yudi Firmanul Arifin1,2, Siti Hamidah1,2, Sudin Panjaitan1,3 , and Eko Suhartono2,4
1.Study Program of Forestry Lambung Mangkurat University, Banjarbaru, South Kalimantan, Indonesia
2.Consortium of Sustainable Tropical Forest Management, Banjarbaru, South Kalimantan, Indonesia
3.Forestry Research Center, Banjarbaru, South Kalimantan, Indonesia
4.School of Medicine Lambung Mangkurat University, Banjarmasin, South Kalimantan, Indonesia
Abstract—Gemor (Nothaphoebe cf umbelliflora) is a tree species that found naturally in swampy forest of Sumatra and Kalimantan, Indonesia. The anti-inflammation activity of red gemor plant parts have not been investigated, therefore many study should be performed. Thus our study aimed to investigate the anti-inflammation effect of different parts of red gemor. Phytochemical analysis of diffrent parts of red gemor extracts revealed the presence of various biochemical compounds such as alkaloids, flavonoids, phenolic compounds, triterpenoids and steroid. The anti-inflammatory activities was determined by inhibition protein denaturation method. Result of this study revealed there is inhibitory action on protein denaturation. The percentage inhibition varied from 20,154 to 71,667 for highest concentration to the lowest concentration. The IC50 was found to be 60 for twig, 47,8 for bark, and 116,2 for leaves of red gemor. To determined which one of the phytochemical constituent in diffrent parts of red gemor are most influence in anti-inflammation activity, we used linear correlation between IC 50 with alkaloid and flavonid content in different parts of red gemor. The result suggest that flavonoid are the most influence to protein denaturation (R2 = 0,9927). The results of the present study suggest that the diffrent parts of red gemor have anti-inflammation activity. The anti-inflammation activity of different parts of red gemor due to the phytochemical constituents content in different parts of red gemor, such as flavonoid and alkaloid.

Index Terms—flavonoid, alkaloid, anti-inflammation activity, nothaphoebe cf umbelliflora.

Cite: Yudi Firmanul Arifin, Siti Hamidah, Sudin Panjaitan, and Eko Suhartono, "In Vitro Anti-Inflammatory Activities of Red Gemor (Nothaphoebe cf Umbelliflora)," Journal of Medical and Bioengineering, Vol. 4, No. 4, pp. 312-317, August 2015. Doi: 10.12720/jomb.4.4.312-317
Copyright © 2013-2016 Journal of Medical and Bioengineering. All Rights Reserved
E-mail: jomb@ejournal.net