Abstract—The fast development of micro-electro-mechanical system (MEMS) technology has brought many great ideas in the field of biomedical applications. A biosensor is a chemical sensing device in which a biologically derived recognition analyte coupled to a transducer to allow the quantitative development of biochemical parameter. A biosensor consists of a bio-element and a sensor-element. The bio-element may be an enzyme, antibody, living cells, tissue, etc., and the sensing element may be electric current, electric potential, and so on and specificity of analyte is the important concept in biosensor. In this paper we review the principle of microcantilever, biosensing mechanism and applications of microcantilevers for bio detection for early detection of diseases accurately. Biosensors can have a variety of biomedical, industry, and military applications. The main advantages of MEMS based sensors are specificity, portability, simplicity, high sensitivity, potential ability for real-time and on-site analysis coupled with the high speed and low cost.

Index Terms—microcantilevers, principle, mechanism of biosensors, biodetection applications, MEMS

Cite: P. G. Gopinath, V. R. Anitha, and S. Aruna Mastani, "Microcantilever based Biosensor for Disease Detection Applications," Journal of Medical and Bioengineering, Vol. 4, No. 4, pp. 307-311, August 2015. Doi: 10.12720/jomb.4.4.307-311